摘要:I NTRODUCTION : The purpose of this clinical report was to describe the restoration of function, phonation and esthetics in a patient that have received radiotherapy and chemotherapy through an application of a tooth-supported overdenture prosthesis. C ASE R EPORT : A 52-yr-old man undergone radiotherapy and chemotheraphy was referred to the Prosthetic Department for the restoration of his lost teeth. All remaining teeth were endodontically treated (tooth number 13, 23, 27, 33, 43) and a tooth-supported overdenture prosthesis was made for both jaws. Briefly, post spaces were prepared and impression of the spaces were taken. Single-unit post and the primary crown for each tooth were prepared and cemented onto the teeth. Secondary crowns adapting the primary crowns were prepared and soldered to the denture framework. After a try-on, the prostheses were given to the patient. No complication (including pain, fracture of the prosthesis or the teeth, joint problem, lack of phonation, etc) was found at a 2-yr clinical follow-up. The prostheses exhibited good retention and stability and the patient was satisfied with the prostheses. C ONCLUSION : Tooth-supported overdenture prosthesis, providing good retention and stability, is a useful alternative in the restoration of the lost function, phonation and esthetics in patients receiving chemotheraphy and radiotherapy.