摘要:OBJECTIVE: The aim of this in vitro study was to compare the shear bond strengths of a self-etch adhesive with two different multi-mode adhesive systems which can also be used as self-etch adhesive. MATERIALS AND METHOD: In this study, 36 extracted human molar teeth were used. The teeth were embedded in acrylic molds. In order to obtain flat dentin surfaces, the occlusal enamel surfaces of the teeth were abraded. Then, to obtain standard smear layer, surfaces were polished with 200 and 600 grid sandpaper under running water. The samples were randomly divided into 3 groups (n=12) according to the adhesive systems: Group 1: Single Bond Universal (universal adhesive), Group 2: All Bond Universal (universal adhesive), Group 3: Clearfil SE Bond (self-etch adhesive). Composite resin cylinders (radius=2 mm, height=2 mm; Tetric N Ceram) were bonded to the adhesive applied surfaces by using teflon molds. After storing in distilled water for 24 h, a shear load was applied to the samples using an Instron universal test machine at a cross-head speed of 0.5 mm/min until failure occurred. Shear bond strength values were calculated. Data were analyzed by using One-Way Variance analysis (ANOVA) and Tukey HSD tests. The level of statistical significance was set to p=0.05. RESULTS: The shear bond strength values of Single Bond Universal and Clearfil SE groups were not significantly different (p>0.05). The All Bond Universal group showed significantly lower bond strength values than the other groups (p<0.05). CONCLUSION: When Single Bond Universal was used as a self-etch system, it showed similar shear bond strength to Clearfil SE Bond, an adhesive accepted as the gold standard among self-etch adhesive systems.