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  • 标题:Microbiome analysis – from technical advances to biological relevance
  • 本地全文:下载
  • 作者:Michelle I. Smith ; Williams Turpin ; Andrea D. Tyler
  • 期刊名称:F1000 Biology Reports
  • 电子版ISSN:2051-7599
  • 出版年度:2014
  • 卷号:6
  • DOI:10.12703/P6-51
  • 语种:English
  • 出版社:Faculty of 1000 Ltd
  • 摘要:The development of culture-independent techniques and next-generation sequencing has led to a staggering rise in the number of microbiome studies over the last decade. Although it remains important to identify the taxa of microbes present in a variety of environmental samples, including the gut microbiomes of healthy and diseased individuals, the next stage of microbiome research will need to focus on uncovering the role of the microbiome rather than its mere composition. Here, we introduce techniques that go beyond identifying the taxa present within a sample and examine the biological function of the microbiome or the host-microbiome interaction.
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