首页    期刊浏览 2025年06月14日 星期六
登录注册

文章基本信息

  • 标题:Genetic screening for metabolic and age-related complications in HIV-infected persons
  • 本地全文:下载
  • 作者:Philip E Tarr ; Amalio Telenti
  • 期刊名称:F1000 Biology Reports
  • 电子版ISSN:2051-7599
  • 出版年度:2010
  • 卷号:2
  • DOI:10.3410/M2-83
  • 语种:English
  • 出版社:Faculty of 1000 Ltd
  • 摘要:Genetic screening for HIV-related complications is emerging as a clinically relevant prediction tool. A number of single nucleotide polymorphisms associated with conditions such as dyslipidemia and type 2 diabetes have been identified in both the general population and in HIV-infected individuals. Additionally, genome-wide association studies have looked at hepatitis C susceptibility in HIV-infected people, and genetic studies are ongoing for coronary artery disease, osteoporosis, and neurocognitive dysfunction. To date, understanding the contribution of genetic variation to the pathogenesis of lipoatrophy and kidney disease in HIV-infection is limited.
国家哲学社会科学文献中心版权所有