期刊名称：Revue de Neuropsychologie Neurosciences Cognitives et Cliniques
印刷版ISSN：2101-6739
电子版ISSN：2102-6025
出版年度：2016
卷号：8
期号：3
页码：192-200
DOI：10.1684/nrp.2016.0392
出版社：John Libbey Eurotext
摘要：Improvements of neuro-oncologic treatments during the last decades resulted in longer survival of patients and thus associated side effects became more visible. Among these side effects, cognitive impairments are ones of the most important and are closely linked to health-related quality-of-life decrements. Consequently, its consideration became of high importance in clinical trials as well as in individual follow-up. Indeed, cognitive defects represent an early marker of tumour progression and/or recurrence at the early stages of the brain tumour but can also be related to treatments’ neurotoxicity that clinicians have to consider in long survivors. The objective of this communication is to briefly present anti-tumour and concomitant treatment-related cognitive impairments. Then, we expose major bias encountered in neuropsychology in this context and present the Grec-Onco cognitive battery, which is currently used in different clinical trials.
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