首页    期刊浏览 2024年07月19日 星期五
登录注册

文章基本信息

  • 标题:An immuno-eco-epidemiological model of competition
  • 本地全文:下载
  • 作者:Souvik Bhattacharya ; Maia Martcheva
  • 期刊名称:Journal of Biological Dynamics
  • 印刷版ISSN:1751-3758
  • 电子版ISSN:1751-3766
  • 出版年度:2016
  • 卷号:10
  • 期号:1
  • 页码:314-341
  • DOI:10.1080/17513758.2016.1186291
  • 出版社:Taylor & Francis
  • 摘要:This paper introduces a novel immuno-eco-epidemiological model of competition in which one of the species is affected by a pathogen. The infected individuals from species one are structured by timesince-infection and the within-host dynamics of the pathogen and the immune response is also modelled. A novel feature of the model is the impact of the species two numbers on the ability of species one to mount an immune response. The within-host model has three equilibria: an extinction equilibrium, pathogen-only equilibrium and pathogen and immune response equilibrium which exists if the immune response reproduction number R0 > 1. The extinction equilibrium is always unstable, the pathogen-only equilibrium is stable if R0 < 1, and the coexistence equilibrium is stable whenever it exists. The between-host competition model has six equilibria: an extinction equilibrium, three disease-free equilibria: species oneonly equilibrium, species two-only equilibrium and a disease-free species coexistence equilibrium. There are also two disease-present equilibria: species one-only disease equilibrium and disease coexistence equilibrium. The existence and stability of these equilibria are governed by six reproduction numbers. Results show that for a nonfatal disease, the disease coexistence equilibrium is stable whenever it exists.
  • 关键词:Immunology; epidemiology; ecology; competition; multiscale modeling; immuno-eco-epidemiology
国家哲学社会科学文献中心版权所有