摘要:The aim of this study is to analyze the risk of transmission, via time/spatial model, of the confirmed cases of dengue in the municipalities belonging to the Pantanal of Mato Grosso. We considered the cases of dengue confirmed and the original inhabitant recorded in the period from 2009 to 2011 at the Information System for Notifiable Diseases (SINAN) in the epidemiological Vigilance – Cuiabá and the Cáceres Regional Health. Three measures of risk time/spatial were used: frequency, duration and intensity, managed in the software ArcGIS 9.2, ESRI. Moran´s Global and Local index were used to evaluate the spatial autocorrelation of the three index. In the period studied, the cities of Cáceres, Poconé, Santo Antônio de Leverger and Nossa Senhora do Livramento presented the highest rates of frequency, duration and intensity, however, Cáceres showed the highest risk of the disease. Moran´s Global Index showed low correlation and Moran´s Local Index showed clusters in some cities according to the index used. These indexes may be useful in the authorities decision and public health. Key words: geo, geohealth, epidemiology, Pantanal Biome.