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标题：Binding Studies and Effect of Light on the Conductance of Intercalated Curcumin into DNA
其他标题：Binding Studies and Effect of Light on the Conductance of Intercalated Curcumin into DNA
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作者：M. A. Subhan ; M. M. Islam ; M. R. U. Chowdhury 等
期刊名称：Journal of Scientific Research
印刷版ISSN：2070-0237
电子版ISSN：2070-0245
出版年度：2012
卷号：4
期号：2
页码：411
DOI：10.3329/jsr.v4i2.8482
语种：English
出版社：Rajshahi University
摘要：Curcumin is one of the most valuable ingredients for scientific research in view of medicinal and therapeutic importance. Curcumin is reported to have antitumor and anticancer activities. It can easily be extracted from Turmeric by solvent extraction methods. At first, dye was extracted through reflux and trituration process. Then curcumin was isolated from dye using column chromatography, which was investigated by infrared spectroscopy and melting point. Curcumin formed a complex with Ce3+, Ce(C21H20O6)n, which was confirmed by comparing the IR spectrum of complex with that of ligand. We observed the effect of light on the curcumin intercalated into DNA and found that the electrons in curcumin excited by absorption of light and the conductance of the solution increased gradually when irradiated by UV-light. The result may indicate the electron conducting property of DNA in solution. We focused on the binding of curcumin with DNA. Our investigations also showed that both curcumin and Ce3+ complex have luminescence properties upon irradiation by UV-light.Keywords: Curcumin; Ce3+-Complex; Luminescence; DNA; Antioxidant.© 2012 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v4i2.8482 J. Sci. Res. 4 (2), 411-418 (2012)
关键词：Chemistry;Curcumin; Ce3+-Complex; Luminescence; DNA; Antioxidant.