文章基本信息
- 标题：Synthesis of Biheterocycles Containing Indole Nucleus and Their Antibacterial Activity
- 本地全文：下载
- 作者：S. Jain ; B. N. Reddy ; K. S. Rao 等
- 期刊名称：Journal of Scientific Research
- 印刷版ISSN：2070-0237
- 电子版ISSN：2070-0245
- 出版年度：2011
- 卷号：4
- 期号：1
- 页码：273
- 语种：English
- 出版社：Rajshahi University
- 摘要：Indole-3-carboxaldehydes (1a-d) undergo condensation with ethyl cyanoacetate and malononitrile to give the acrylonitrile 2a-d and 3a-d which on reaction with hydrazine hydrate yield 3,5-diamino-5-hydroxy-4-(3-indolylmethylene)pyrazoles (4a-d) and 3-amino-5-hydroxy -4-(3-indolylmethylene)pyrazoles (5a-d), respectively. The new compounds were also screened for their antibacterial activity. Keywords : Indole-3-carboxaldehydes ; Active methylene compounds; Base; Hydrazine hydrate; Pyrazoles. © 2012 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. doi: http://dx.doi.org/10.3329/jsr.v4i1.7821 J. Sci. Res. 4 ( 1), 273-278 (2012)
- 关键词：Indole-3-carboxaldehydes;Active methylene compounds;Base;Hydrazine hydrat;, Pyrazoles
