文章基本信息

标题：Negative Inotropic and Chronotropic Effects of Phenolic Fraction from Cynodon dactylon (linn) on Isolated Perfused Frog Heart
其他标题：Negative Inotropic and Chronotropic Effects of Phenolic Fraction from Cynodon dactylon (linn) on Isolated Perfused Frog Heart
本地全文：下载
作者：M. Mohamed Shabi ; C. David Raj ; C. Sasikala 等
期刊名称：Journal of Scientific Research
印刷版ISSN：2070-0237
电子版ISSN：2070-0245
出版年度：2012
卷号：4
期号：3
页码：657-663
DOI：10.3329/jsr.v4i3.8549
语种：English
出版社：Rajshahi University
摘要：Cynodon dactylon (L.) Pers belongs to the family Poaceae is a grass native to North Africa, Asia and Australia and southern Europe. The phenolic fraction of Cynodon dactylon (Linn) (CDP) was evaluated for its cardio-protective activity using isolated frog´s heart perfusion method. The negative inotropic and chronotropic activities were recorded using kymograph. The CDP produced negative inotropic and chronotropic actions on isolated frog heart. The pharmacological effect was selectively inhibited by atropine indicating that these might have been mediated through muscarinic receptor.© 2012 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v4i3.8549 J. Sci. Res. 4 (3), 657-663 (2012)
关键词：Pharmacy; Pharmacology;Cynodon dactylon; Hydroquinone; GC-MS; Inotropic; Chronotropic