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标题： Synthesis and Characterization of Some Mixed Ligand Complexes of Zn(II) with 4, 4´- Bipyridine: Anti-inflammatory and Analgesic Activities of these Complexes 其他标题： Synthesis and Characterization of Some Mixed Ligand Complexes of Zn(II) with 4, 4´- Bipyridine: Anti-inflammatory and Analgesic Activities of these Complexes 本地全文： 下载 作者： M. A. Hossain ; M. A. Alam ; R. Zahan 等期刊名称： Journal of Scientific Research 印刷版ISSN： 2070-0237 电子版ISSN： 2070-0245 出版年度： 2014 卷号： 6 期号： 2 页码： 309-318 DOI： 10.3329/jsr.v6i2.16994 语种： English 出版社： Rajshahi University 摘要： The mixed ligand complexes of Zn(II) with 4,4-bipyridine and some organic acids or amino acids were prepared in the solid form and characterized by elemental analysis, conductivity, magnetic moment measurement, IR, 1H-NMR, 13C-NMR and FAB+ mass studies. To study anti-inflammatory and analgesic activities of these complexes, some Swiss albino mice of 5-7 weeks old were taken. One dose of the test compounds of 10 mg/kg was selected throughout the research work. The anti-inflammatory activity of the test compounds were determined by carrageenan induced mice paw edema inhibition method. The analgesic activity was determined by acetic acid induced writhing methods. These three compounds showed positive effects as anti-inflammatory and analgesic agents. Anti- inflammatory and analgesic activities of the test compounds at 50 mg/kg were quite comparable to those of standard drugs at 10 mg/kg. Keywords: Zinc; Organic acids; 4, 4'-Bipyridine; Anti-inflammatory; Analgesic activity. © 2014 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. doi: http://dx.doi.org/10.3329/jsr.v6i2.16994 J. Sci. Res. 6 (2), 309-318 (2014) 关键词： Chemistry & Pharmacy;Zinc; Organic acids; 4; 4'-Bipyridine; Anti-inflammatory; Analgesic activity.
