文章基本信息

标题：Biological Activity Study on a Malvaceae Plant: Bombax ceiba
其他标题：Biological Activity Study on a Malvaceae Plant: Bombax ceiba
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作者：M. K. Islam ; J. A. Chowdhury ; I. Z. Eti 等
期刊名称：Journal of Scientific Research
印刷版ISSN：2070-0237
电子版ISSN：2070-0245
出版年度：2011
卷号：3
期号：2
页码：445-450
DOI：10.3329/jsr.v3i2.5162
语种：English
出版社：Rajshahi University
摘要：The work described in this paper details the biological investigation on Bombax ceiba, species of Malvaceae. The methanol crude extract of Bombax ceiba was fractionated with kupchan method and n-hexane, carbon tetrachloride, chloroform fraction were made for screening the antimicrobial and antitumor potentials using disc diffusion method and brine shrimp lethality bioassay respectively. An established antibiotic (kanamycin, 30µg/disc) and cytotoxic agent (vincristine sulphate) were used to compare the results. From the graphs the concentration of methanolic crude extract give LC50 (50% mortality) value of 3.90mg/ml. LC90 was also determined from the graph to establish the therapeutic index and the value was found 150.0mg/ml. The four fractions were assayed for antimicrobial screening and the carbon tetrachloride fraction showed most prominent zone of inhibition against a number of bacterial and fungal strains.Keywords: Bombax ceiba; Brine shrimp lethality bioassay; Disc diffusion method.© 2011 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi:10.3329/jsr.v3i2.5162 J. Sci. Res. 3 (2), 445-450 (2011)
关键词：Pharmacy; Biology;Bombax ceiba; Brine shrimp lethality bioassay; Disc diffusion method.