Allocating infection: the political economy of the swine flu (H1N1) vaccine.
Ryan, Matt E.
CDC's Advisory Committee on Immunization Practices (ACIP) recommends that certain groups of the population receive the 2009 H1N1 flu vaccine first. These target groups include pregnant women, people who live with or care for infants younger than 6 months of age, healthcare and emergency medical services personnel with direct patient contact, infants 6 months through young adults 24 years of age (especially children younger than 5 years of age), and adults 25 through 64 years of age who are at high risk for 2009 H I N1 complications because of chronic health disorders or compromised immune systems:
APPENDIX
TABLE A1
Evolution of Swine Flu Vaccine Allocation
Dependent Variable: Total Doses
of Swine Flu Vaccine Shipped per
1000 residents
Week 1 Week 2 Week 3 Week 4 Week 5
House committee
members
Democrat 0.79 0.01 0.28 -1.07 1.29
(0.50) (0.46) (0.61) (0.69) (1.19)
Republican -3.29 ** 0.51 -0.57 1.03 -1.71
(1.42) (1.50) (2.26) (3.04) (4.11)
Senate committee
members
Democrat -1.52 1.86 0.79 -1.38 2.19
(2.43) (2.69) (3.70) (5.15) (6.85)
Republican 6.01 ** 3.14 -0.63 -5.21 3.07
(2.25) (1.93) (4.06) (5.58) (5.61)
N 51 51 51 51 51
[R.sup.2] 0.20 0.04 0.01 0.03 0.02
Dependent Variable: Total Doses
of Swine Flu Vaccine Shipped per
1000 residents
Week 6 Week 7 Week 8 Week 9
House committee
members
Democrat -1.74 0.16 -1.30 1.22
(1.28) (1.68) (2.17) (2.70)
Republican 2.40 -0.75 3.68 1.26
(4.09) (0.56) (6.22) (6.91)
Senate committee
members
Democrat 2.27 5.98 13.91 3.57
(6.71) (9.19) (9.63) (10.30)
Republican -0.27 3.70 10.97 12.58 **
(4.92) (7.11) (6.74) (7.13)
N 51 51 51 51
[R.sup.2] 0.05 0.02 0.10 0.03
Notes: Robust standard errors in parentheses.
** Significant at 1% level; ** significant at 5% level;
* significant at 10% level (estimations weighted by population).
TABLE A2
Evolution of Swine Flu Vaccine Allocation
Dependent Variable: Total Doses
of Swine Flu Vaccine Shipped
Week 1 Week 2 Week 3
House committee members
Democrat 26475.0 * 35528.4 * 70760.5 ***
(15286.1) (18907.3) (20765.9)
Republican 110.8 49082.2 53478.8
(15411.79) (29564.1) (37819.9)
Chair, House 329033.0 *** 223992.7 292772.0
committee (74144.7) (150399.8) (193784.4)
Senate committee members
Democrat 2730.6 14929.1 8796.1
(14252.4) (17138.2) (23738.4)
Republican (16546.3) -891.0 -22964.3
(10998.1) (17229.8)
Chair, Senate -30205.0 ** -4054.2 -59237.2 ***
Committee (14394.4) (17031.4) (17331.4)
Population 8.71 *** 21.75 *** 33.02 ***
(thousands) (2.67) (5.44) (6.90)
N 51 51 51
[R.sup.2] 0.87 0.96 0.96
Dependent Variable: Total Doses
of Swine Flu Vaccine Shipped
Week 4 Week 5 Week 6
House committee members
Democrat 42570.1 43491.4 17634.1
(29179.2) (41829.8) (38777.9)
Republican 63743.7 55041.8 107285.2
(68263.5) (86337.6) (89592.2)
Chair, House 173800.8 735030.5 428324.2
committee (346251.2) (447173.3) (456655.5)
Senate committee members
Democrat -4966.7 30853.6 27135.9
(36920.4) (49095.2) (50506.4)
Republican -44017.3 -10952.4 -31947.8
(27702.4) (28679.4) (27527.2)
Chair, Senate -20630.8 -75510.1 21359.1
Committee (33036.4) (48806.8) (46568.3)
Population 65.76 *** 89.46 *** 116.11 ***
(thousands) (13.07) (17.22) (17.22)
N 51 51 51
[R.sup.2] 0.96 0.97 0.98
Dependent Variable: Total Doses
of Swine Flu Vaccine Shipped
Week 7 Week 8 Week 9
House committee members
Democrat 74659.8 29577.5 6830.7
(46875.8) (61447.5) (60404.0)
Republican 117551.6 179898.4 158110.1
(113290.9) (137212.3) (143232.9)
Chair, House 889209.8 927572.1 1025735.1
committee (583318.7) (708957.7) (736750.1)
Senate committee members
Democrat 60460.1 115263.8 59492.4
(66620.7) (79292.2) (78547.2)
Republican -25015.1 1120.6 1120.4
(38194.8) (44810.1) (45633.7)
Chair, Senate -91732.2 -37767.3 15686.1
Committee (61604.5) (74108.5) (69437.5)
Population 125.60 *** 154.48 *** 195.36 ***
(thousands) (21.35) (26.88) (26.79)
N 51 51 51
[R.sup.2] 0.98 0.97 0.98
Notes: Robust standard errors in parentheses.
*** Significant at 1%; ** significant at 5%;
* significant at 10% level.
TABLE A3
Pairwise Correlations Between Political and Risk Factors
House Committee Members
Democrat Republican
Birth rate -0.0096 0.0987
(.9465) (.4906)
Percentage of population 0.1378 0.2518 *
under 5 years of age (.3351) (.0747)
Percentage of population 0.2035 0.1994
from 5 to 13 years of age (.1521) (.1606)
Percentage of population 0.1565 0.0335
from 14 to 17 years of age (.2728) (.8157)
Percentage of population 0.0196 0.0009
from 18 to 24 years of age (.8916) (.9949)
Percentage of population 0.1552 0.1680
under 24 years of age (.2768) (.2387)
Percentage of population -0.1851 -0.0969
over 65 years of age (.1936) (.4987)
Nurses per capita -0.2037 -0.2031
(.1517) (.1529)
Doctors per capita 0.0750 -0.1540
(.6009) (.2807)
Nurses and Doctors per -0.1114 -0.2025
capita (.4365) (.1541)
Hospital beds per capita -0.2871 ** -0.0927
(.0410) (.5175)
H1N1 mortality rate
Week 1 -0.0003 0.2168
(.9983) (.1264)
Week 2 -0.0248 0.0167
(.8627) (.9074)
Week 3 -0.2358 * -0.0178
(.0958) (.9011)
Week 4 -0.2179 -0.1317
(.1245) (.3570)
Week 5 -0.1628 -0.0802
(.2536) (.5756)
Week 6 -0.1156 -0.0516
(.4192) (.7194)
Week 7 -0.1922 -0.1835
(.1767) (.1973)
Week 8 -0.0957 -0.1135
(.5039) (.4278)
Week 9 -0.1453 -0.0975
(.3088) (.4963)
Senate Committee Members
Democrat Republican
Birth rate -0.2169 0.3151 **
(.1263) (.0243)
Percentage of population -0.1789 0.3321 **
under 5 years of age (.2090) (.0173)
Percentage of population -0.0515 0.2982 **
from 5 to 13 years of age (.7194) (.0336)
Percentage of population -0.0381 0.2930 **
from 14 to 17 years of age (.7909) (.0369)
Percentage of population -0.0778 0.2893 **
from 18 to 24 years of age (.5875) (.0395)
Percentage of population -0.1101 0.3624 ***
under 24 years of age (.4419) (.0090)
Percentage of population 0.0410 -0.3619 ***
over 65 years of age (.7752) (.0091)
Nurses per capita 0.0814 -0.2504 *
(.5700) (.0764)
Doctors per capita 0.1522 -0.2535 *
(.2862) (.0727)
Nurses and Doctors per 0.1174 -0.2752 *
capita (.4120) (.0507)
Hospital beds per capita -0.2908 ** -0.0901
(.0384) (.5294)
H1N1 mortality rate
Week 1 -0.2478 * 0.1880
(.0796) (.1865)
Week 2 0.0502 0.2749 *
(.7265) (.0509)
Week 3 0.0312 0.0489
(.8280) (.7334)
Week 4 -0.0194 0.1369
(.8924) (.3380)
Week 5 0.0911 0.1250
(.5248) (.3820)
Week 6 0.0835 0.1286
(.5601) (.3684)
Week 7 0.2571 * 0.1343
(.0685) (.3476)
Week 8 -0.1606 -0.1182
(.2602) (.4086)
Week 9 0.3211 ** 0.0166
(.0216) (.9080)
Notes: p values in parentheses.
TABLE 1
Evolution of Swine Flu Vaccine Allocation
Dependent Variable: Total Doses
of Swine Flu Vaccine Shipped
Week 1 Week 2 Week 3
(a)
House committee members
Democrat 63136.1 *** 62196.3 ** 99538.2 ***
(23083.0) (25883.8) (34011.4)
Republican -15336.5 36998.9 39234.1
(21444.9) (26826.4) (34963.5)
Senate committee members
Democrat -11682.5 6307.4 -8384.1
(16237.9) (13759.9) (21684.4)
Republican 32360.6 3064.8 -15827.8
(20391.3) (9446.9) (16759.6)
Percentage of population -6869.4 ** -1368.8 -3181.8
under 24 years of age (3369.2) (2108.8) (4027.9)
First responders -1907.3 -2192.1 -853.9
(2386.6) (2617.1) (3032.9)
Weekly HINT mortality rate 7494.2 -14993.5 -6520.5
(9191.0) (9513.6) (6818.5)
Borders Mexico 39702.6 83551.8 * 79537.3
(45121.7) (42393.6) (52724.6)
Population (thousands) 8.69 ** 20.17 *** 32.47 ***
(3.87) (6.63) (8.74)
N 51 51 51
[R.sup.2] 0.83 0.96 0.96
(b) Only political factors
House committee members
Democrat 54526.1 ** 55415.6 ** 94169.3 ***
(21495.2) (24167.2) (30285.1)
Republican -15814.6 38291.8 39208.5
(21697.3) (28486.2) (35575.6)
Senate committee members
Democrat -10978.1 6849.3 -5857.2
(14377.6) (12438.9) (19921.6)
Republican 25341.2 3963.7 -16038.0
(18212.5) (11373.0) (16873.7)
Population (thousands) 10.51 *** 22.86 *** 34.88 ***
(3.69) (5.80) (7.41)
N 51 51 51
[R.sup.2] 0.82 0.95 0.96
(c) Only risk factors
Percentage of population -1599.9 2925.7 2873.9
under 24 years of age (3287.3) (2388.7) (3696.3)
First responders -539.1 -1699.1 1763.2
(2560.0) (2078.5) (3243.0)
Weekly H 1 N 1 5768.9 -7945.4 -12071.9 *
mortality rate (8740.4) (11272.5) (7160.4)
Borders Mexico 16865.0 67311.0 59248.3
(62065.2) (50394.9) (67311.2)
Population (thousands) 16.19 *** 30.64 *** 47.97 ***
(3.20) (3.26) (4.65)
N 51 51 51
[R.sup.2] 0.76 0.94 0.94
Dependent Variable: Total Doses
of Swine Flu Vaccine Shipped
Week 4 Week 5 Week 6
(a)
House committee members
Democrat 62218.4 124937.1 65882.2
(50585.3) ('78092.1) (71249.2)
Republican 53102.2 21264.4 84995.8
(57556.2) (77028.5) (73869.3)
Senate committee members
Democrat -16981.4 -7893.0 8607.3
(27254.6) (39733.2) (37224.3)
Republican -36815.2 20590.8 -23790.0
(29083.8) (27422.3) (29987.3)
Percentage of population -2314.2 -12560.6 * -3027.2
under 24 years of age (5565.6) (7301.2) (7382.8)
First responders 1273.8 -1234.2 820.6
(5604.1) (6631.1) (6533.5)
Weekly HINT mortality rate -6056.6 -3590.4 -951.9
(5621.3) (9683.2) (6097.7)
Borders Mexico 106002.7 160234.1 142981.1
(95890.4) (146662.4) (136590.1)
Population (thousands) 63.97 *** 88.05 *** 114.18 ***
(14.32) (21.31) (19.59)
N 51 51 51
[R.sup.2] 0.96 0.96 0.98
(b) Only political factors
House committee members
Democrat 57163.1 105770.0 57058.2
(44052.4) (69152.9) (61993.5)
Republican 55317.2 19441.2 86741.5
(55710.2) (79922.5) (77001.0)
Senate committee members
Democrat -12562.6 -380.0 13894.3
(26177.5) (35337.1) (34925.6)
Republican -40062.1 5648.3 -22977.9
(25417.6) (27183.3) (23347.9)
Population (thousands) 66.75 *** 93.56 *** 117.99 ***
(11.81) (17.50) (16.31)
N 51 51 51
[R.sup.2] 0.96 0.96 0.98
(c) Only risk factors
Percentage of population 1079.2 -3479.9 1660.3
under 24 years of age (3387.8) (4132.0) (4561.9)
First responders 3336.1 2321.9 2706.3
(4986.6) (5698.8) (5359.6)
Weekly H 1 N 1 -9110.2 -2706.5 -3303.3
mortality rate (7482.8) (7605.0) (5102.7)
Borders Mexico 100018.3 125080.8 140079.9
(106235.9) (147954.5) (145857.6)
Population (thousands) 75.30 *** 106.00 *** 127.63 ***
(6.20) (9.56) (8.14)
N 51 51 51
[R.sup.2] 0.96 0.96 0.97
Dependent Variable: Total Doses
of Swine Flu Vaccine Shipped
Week 7 Week 8 Week 9
(a)
House committee members
Democrat 169938.1 134114.9 177974.7
(98087.5) (114344.6) (128888.9)
Republican 70365.8 133087.1 79942.5
(96011.8) (115434.1) (131188.4)
Senate committee members
Democrat 27080.0 78042.0 -173.0
(59739.5) (62370.7) (76126.6)
Republican 7.0 23334.5 36972.3
(36910.9) (47275.3) (51058.8)
Percentage of population -8319.1 -15001.9 -1446.9
under 24 years of age (9813.6) (11373.2) (1288.3)
First responders -3413.9 -3712.4 -1957.8
(9257.0) (10300.0) (11200.0)
Weekly HINT mortality rate -16825.1 -23720.6 -19735.3
(17385.7) (19681.5) (48677.2)
Borders Mexico 229949.0 251302.1 405547.1
(187440.4) (224619.8) (276492.3)
Population (thousands) 122.85 *** 151.09 *** 190.74 ***
(27.24) (32.03) (34.90)
N 51 51 51
[R.sup.2] 0.97 0.97 0.98
(b) Only political factors
House committee members
Democrat 149983.6 * 110926.9 147197.2
(84512.9) (101667.5) (120696.5)
Republican 74482.2 135149.9 83226.8
(103495.3) (122047.7) (142248.9)
Senate committee members
Democrat 22645.9 80213.1 6647.4
(48504.3) (53513.5) (56856.0)
Republican -4928.2 21450.4 34399.9
(34472.0) (38288.3) (42178.8)
Population (thousands) 130.56 *** 159.21 *** 202.69
(21.96) (26.50) (29.65)
N 51 51 51
[R.sup.2] 0.97 0.97 0.97
(c) Only risk factors
Percentage of population 3389.2 -3758.2 133.1
under 24 years of age (3792.6) (5570.5) (5899.0)
First responders 3034.3 -134.5 2350.1
(7267.4) (7819.0) (8751.1)
Weekly H 1 N 1 -7806.8 -22497.8 -14523.1
mortality rate (14768.3) (18229.0) (30791.4)
Borders Mexico 187450.6 241255.2 361804.9
(192462.3) (291853.8) (275805.3)
Population (thousands) 150.14 *** 175.77 *** 218.82
(12.64) (14.16) (16.36)
N 51 51 51
[R.sup.2] 0.97 0.97 0.97
Notes: Robust standard errors in parentheses.
*** Significant at 1%; ** significant at 5%;
* significance at 10% level.
TABLE 2
Summary Statistics
Variable For the Following Variables,
N = 51
Mean SD Min Max
Population (in millions) 5.96 6.72 0.53 36.76
House committee members
Democrat 0.69 1.01 0 6
Republican 0.43 0.70 0 3
Senate committee members
Democrat 0.24 0.43 0 1
Republican 0.20 0.40 0 1
Percentage of population under 34.57% 2.30% 30.21% 44.31%
24 years of age
Percentage of population from 18 9.93% 0.73% 8.53% 12.40%
to 24 years of age
Percentage of population from 14 5.81% 0.33% 5.08% 7.08%
to 17 years of age
Percentage of population from 5 12.03% 0.91% 8.75% 15.21%
to 13 years of age
Percentage of population under 5 6.80% 0.77% 5.10% 9.61%
years of age
Percentage of population over 65 12.57% 1.74% 6.66% 17.23%
years of age
Birth rate 13.42 1.68 9.80 19.40
Nurses per 1,000 residents 8.90 1.81 5.81 15.61
Doctors per 1,000 residents 3.21 1.04 2.07 8.57
Beds per 1,000 residents 2.92 0.96 1.70 5.80
Borders Mexico 0.08 0.27 0 1
Influenza activity
Widespread 0.80 0.40 0 1
Regional 0.16 0.37 0 1
HIN1 mortality rate
Week 1 0.35 0.56 0.00 2.41
Week 2 0.31 0.51 0.00 2.02
Week 3 0.64 0.81 0.00 3.10
Week 4 0.99 1.50 0.00 8.70
Week 5 1.03 1.13 0.00 5.17
Week 6 0.83 1.16 0.00 6.22
Week 7 1.35 1.20 0.00 5.54
Week 8 0.70 1.12 0.00 6.20
Week 9 0.51 0.61 0.00 2.11
TABLE 3
Swine Flu Vaccine Allocation, Pooled Analysis
Dependent Variable: Total Doses of
Swine Flu Vaccine Shipped per Week
(1) (2) (3) (4)
House committee
members
Democrat 16355.2 19738.2 19669.6 16319.6
(17662.7) (19141.6) (17699.1) (18119.9)
Republican 9247.4 8893.6 8697.9 10705.4
(14181.5) (13646.3) (12387.6) (11007.1)
Senate committee
members
Democrat 738.6 -898.8 30.9 2366.4
(9513.9) (10119.0) (9525.6) (10616.9)
Republican 3822.2 3927.9 4314.2 5682.7
(9020.4) (11086.8) (10262.2) (12637.2)
Percentage of -1499.7 -1524.8 -1729.4
population under (1985.5) (1893.5) (2387.0)
24 years of age
First responders -193.1 -405.6 2234.3
(1185.7) (1267.0) (1924.8)
Weekly H1N1 -458.8 -4536.8 ** 5280.4 **
mortality rate (1769.9) (2148.0) (2164.0)
Borders Mexico 43987.6 47264.8 72754.9 *
(33234.4) (30393.4) (42059.1)
Population 22.52 *** 21.24 *** 21.09 *** 21.39
(thousands) (2.52) (2.59) (2.33) (2.35)
N 459 459 459 459
[R.sup.2] 0.72 0.73 0.77 0.77
Notes: Robust standard errors in parentheses.
*** Significant at 1%; ** significant at 5%;
* significant at 10% level.
TABLE 4
Initial Distribution of Swine Flu Vaccine--Age Factors
Dependent Variable: Total Doses
of Swine Flu Vaccine Shipped
(1) (2) (3) (4)
Political factors
House committee
members
Democrat 57441.7 ** 63356.7 ** 63759.7 ** 60454.4 **
(23820.4) (25116.3) (24765.1) (24954.9)
Republican -16332.4 -140_56.5 -14977.2 -16093.0
(22123.7) (21196.2) (21499.0) (22473.0)
Senate committee
members Democrat -12761.1 -10738.9 -11003.9 9646.8
(17610.0) (16875.3) (17042.0) (17260.9)
Republican (20857.9) ('20844.9) (20034.1) (20751.6)
27465.8 30892.9 31135.9 28185.5
CDC control factors
Ace factors
Birth rate -7662.6
(6397.5)
Percentage of -6585.0 *
population under (3645.3)
24 years of age
Percentage of -20996.2 *
population from (10935.4)
18 to 24 years
of age
Percentage of -24439.0
population from (20198.5)
14 to 17 years
of age
Percentage of
population from
5 to 13 years of
age
Percentage of
population under
5 years of age
Percentage of
population over
65 years of age
First responders -2062.7 -2659.4 -943.0 -905.0
(2744.9) (2835.1) (2663.1) (2631.3)
Prevalence of flu
Weekly HIM 6800.4 5879.2 4027.2 5385.9
mortality rate (10211.0) (10456.2) (10703.3) (10540.6)
Widespread -19196.8 -4715.9 -15618.9 601.6
(22546.5) (21473.2) (21530.2) (21086.5)
Regional -36511.2 -17109.1 -33034.1 -3282.2
(33450.2) (25250.8) (27857.9) (22453.2)
Population 10.05 ** 9.28 ** 9.04 ** 9.70 **
(thousands) (4.07) (4.20) (4.22) (4.21)
N 51 51 51 51
[R.sup.2] 0.83 0.83 0.83 0.83
Dependent Variable: Total Doses
of Swine Flu Vaccine Shipped
(5) (6) (7)
Political factors
House committee
members
Democrat 63061.7 ** 57509.8 ** 59989.1 **
(25306.3) (23875.13) (25484.2)
Republican -14091.4 -14913.3 -16043.6
(21221.4) (21582.0) (21948.3)
Senate committee
members Democrat -9784.5 -10352.8 -8708.1
(16854.8) (16773.6) (16920.4)
Republican (20132.6) (21123.7) (23590.6)
27297.4 28097.2 29493.4
CDC control factors
Ace factors
Birth rate
Percentage of
population under
24 years of age
Percentage of
population from
18 to 24 years
of age
Percentage of
population from
14 to 17 years
of age
Percentage of -17554.9
population from (11650.7)
5 to 13 years of
age
Percentage of -15107.5
population under (13210.0)
5 years of age
Percentage of 4774.6
population over (5331.7)
65 years of age
First responders -3353.0 -2380.0 -12994
(3258.0) (3000.4) (2651.9)
Prevalence of flu
Weekly HIM 7219.7 7478.4 5239.8
mortality rate (10516.5) (10040.2) (10734.7)
Widespread 21941.9 -19948.8 -8560.6
(26913.3) (24417.9) (21645.5)
Regional 14767.5 -30482.6 -14321.2
(28063.8) (32324.9) (25344.6)
Population 9.28 ** 10.25 ** 9.86 **
(thousands) (4.23) (4.01) (4.21)
N 51 51 51
[R.sup.2] 0.83 0.83 0.83
Notes: Robust standard errors in parentheses.
** Significant at 1%; ** significant at 5%;
* significant at 1090 level.
TABLE 5
Initial Distribution of Swine Flu Vaccine--First Responders
Dependent Variable: Total Doses
of Swine Flu Vaccine Shipped
(8) (9) (10) (11)
Political factors
House committee
members
Democrat 63356.7 ** 63056.5 ** 63250.3 ** 62547.5 **
(25116.3) (25022.6) (25221.0) (24761.7)
Republican -14056.5 -13773.7 -15023.0 -12824.5
(21196.2) (21306.2) (20677.7) (21005.0)
Senate committee
members
Democrat -10738.9 -11680.7 -8960.5 -21496.3
(16875.3) (16799.1) (17856.9) (18921.9)
Republican 30892.9 30381.9 32748.6 26563.3
(20844.9) (20705.2) (21229.4) (20897.5)
CDC control factors
Percentage of -6585.0 * -6402.8 * -6455.1 * -7028.1 *
population under (3645.3) (3660.1) (3586.8) (3776.1)
24 years of age
First responders
Nurses and doctors -2659.4
per capita (2835.1)
Nurses per capita -3112.1
(3556.7)
Doctors per capita -7884.5
(10700.0)
Beds per capita -13500.0 *
(7697.8)
Prevalence of flu
Weekly H1N1 5879.2 6456.4 5373.7 8699.7
mortality rate (10456.2) (10498.4) (10399.7) (9977.1)
Widespread -4715.9 3029.7 -16903.1 2633.9
(21473.2) (16083.2) (40132.5) (18690.1)
Regional -17109.1 -11285.5 -25923.3 -24160.9
(25250.8) (20341.4) (38204.6) (24014.1)
Population 9.28 ** 9.21 ** 9.63 ** 8.87 **
(thousands) (4.20) (4.23) (4.01) (4.20)
N 51 51 51 51
[R.sup.2] 0.83 0.83 0.83 0.84
Notes: Robust standard errors in parentheses.
*** Significant at 1%; ** significant at 5%;
* significant at 10% level.