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  • 标题:CERCETAREA UNOR CĂI DE SINTEZĂ A IZOTIOCIANATOCHALCONELOR
  • 本地全文:下载
  • 作者:Nicanor BARBĂ ; Galina DRAGALINA ; Ana POPUŞOI
  • 期刊名称:Studia Universitatis Moldaviae: Stiinte Sociale
  • 印刷版ISSN:1814-3199
  • 电子版ISSN:2345-1017
  • 出版年度:2008
  • 卷号:7
  • 期号:17
  • 页码:154-158
  • 出版社:Moldova State University
  • 摘要:Different methodes of izothiocyanatochalcones′ synthesis were studied. Good results give the method which includes condensation of N,N-dimethylthioureidoacetophenones with aromatic aldehydes, followed by elimination of dimethyl- amine from the corresponding chalcone when it is being treated with acetic anhydride in the case of 4-dimethylamino-3′ and 4′-N,N-dimethylthioureidochalcones. Direct condensation of 4-dimethylaminobenzaldehyde with 4-izothiocyanato- acetophenone in the presence of acid catalyst gives a chalcone yield of 91%
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