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  • 标题:Pharmacovigilance and tuberculosis: applying the lessons of thioacetazone
  • 本地全文:下载
  • 作者:Dennis Falzon ; Geraldine Hill ; Shanthi N Pal
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:2014
  • 卷号:92
  • 期号:12
  • 页码:918-919
  • DOI:10.2471/BLT.14.142570
  • 出版社:World Health Organisation
  • 摘要:Following its introduction in the late 1940s, thioacetazone was widely-used as an anti-tuberculosis medicine in the following decades. 1 Reports of cutane- ous hypersensitivity reactions related to its use emerged in the literature soon after its introduction and by the early 1970s the association between the medi- cine and the adverse drug reaction was well established. 2 Despite the increased recognition of this risk, thioacetazone remained in use mainly in low-income countries becaus e of its low cost
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