Counselling of patients with viral hepatitis is often limited to discussions about how the virus is transmitted. The aim of the present study was to document the principal concerns of patients suffering from chronic hepatitis B and C infection. The most common volunteered concerns were infecting family members (80.6%), infecting others (66.7%), side-effects of treatment (50.0%), disease progression to cirrhosis (44.4%), loss of employment (41.7%), liver transplantation (36.1%), social stigma (36.1%), change in lifestyle (33.3%), development of liver cancer (25%), costs and money (22.2%), fear of disease (5.6%) and psychological disease (5.6%). Health care providers who focus counselling efforts exclusively on viral transmission are unlikely to address other important concerns.