This research is focused on life satisfaction and coping strategies of women undergoing their first IVF treatment. The aim was also to find coping strategies which are adaptive or non-adaptive for this situation. The sample of 139 women filled in two questionnaires: Life satisfaction questionnaire (Fahrenberg, Myrtek, Schumacher, & Brahler, 2001) and COPE Inventory (Carver, Scheier, & Weintraub, 1989) at the beginning of their treatment. Results show that women are most satisfied with their partnership, housing and sexuality in compared with other aspects of life satisfaction, and they are at least satisfied with their leisure time and financial state. From coping strategies they use the most often Planning, Positive reinterpretation and active coping. As adaptive coping strategies we found Seeking of social support and Positive reinterpretation, on the contrary we found coping strategy Denial not adaptive. There are some useful implications forms this research for psychological counseling for women undergoing IVF treatment.