期刊名称：Epidemiology, Biostatistics and Public Health
印刷版ISSN：2282-0930
出版年度：2012
卷号：9
期号：4
语种：English
出版社：PREX
摘要：The problem of estimating the power of the multivariate Intersection Union test (IUT) is studied. Four classical parametric solutions and a bootstrap non-parametric one, providing statistical lower bounds (i.e. one directional confidence intervals) for the power, are considered. The performances of these techniques in several bivariate IUT settings are compared through a simulation study. All solutions are biased, since their actual coverage probabilities are higher than the nominal one. The bootstrap solution shows the smallest bias, and the variability of its estimates is the lowest. Moreover, the bias of the bootstrap solution reduces faster than those of the other techniques when the pilot sample size, or the correlation, or the rate between the two non-centrality parameters increases. Also, the non-parametric bootstrap solution can be improved by calibration, with a considerable bias reduction.
