文章基本信息

标题：The potential role of regenerative medicine in the management of traumatic patients
作者：Moradi, Mahmoudreza ; Hood, Brandy ; Moradi, Marziyeh 等
期刊名称：Journal of Injury and Violence Research
印刷版ISSN：2008-2053
电子版ISSN：2008-4072
出版年度：2014
卷号：7
期号：1
页码：27-35
语种：English
出版社：Kermanshah University of Medical Sciences
摘要：Traumatic injury represents the most common cause of death in ages 1 to 44 years and a significant proportion of patients treated in hospital emergency wards each year. Unfortunately, for patients who survive their injuries, survival is not equal to complete recovery. Many traumatic injuries are difficult to treat with conventional therapy and result in permanent disability. In such situations, regenerative medicine has the potential to play an important role in recovery of function. Regenerative medicine is a field that seeks to maintain or restore function with the development of biological substitutes for diseased or damaged tissues. Several regenerative approaches are currently under investigation, with a few achieving clinical application. For example, engineered skin has gained FDA approval, and more than 20 tissue engineered skin substitutes are now commercially available. Other organ systems with promising animal models and small human series include the central and peripheral nervous systems, the musculoskeletal system, the respiratory and genitourinary tracts, and others. This paper will be a clinically oriented review of the regenerative approaches currently under investigation of special interest to those caring for traumatic patients. © 2014 KUMS, All rights reserved
关键词：Trauma;Tissue Engineering;Regenerative medicine