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  • 标题:Seroprevalence of Toxoplasma gondii Among Schizophrenics at Hospital Kajang
  • 作者:Juanah, Lovetta Yatta ; Jalaludin, Juliana ; Osman, Malina
  • 期刊名称:American Journal of Infectious Diseases
  • 印刷版ISSN:1553-6203
  • 出版年度:2013
  • 卷号:9
  • 期号:1
  • 页码:11-16
  • DOI:10.3844/ajidsp.2013.11.16
  • 出版社:Science Publications
  • 摘要:Studies have found a high seroprevalence of T. gondii in schizophrenia patients than controls. This case-control study was done to determine the serprevalence of Toxoplasma gondii and to identify its risk factors among schizophrenia patients at Hospital Kajang. Eighty-eight (88) schizophrenia patients and 88 non-psychiatric controls were examined for the presence of anti- Toxoplasma IgG and IgM antibodies by Enzyme Linked Immunosorbent Assay (ELISA). Questionnaires were used to collect socio-demographic and behavioral data among the respondents. From the results, the seroprevalence of anti- T. gondii IgG antibodies was significantly higher (51.0%) in schizophrenia patients than in controls (30.7%); (OR = 2.01; 95% CI: 2.16-3.01; p = 0.023. There was no significant association between the socio-demographic factors and toxoplasmosis. Beef consumption (p = 0.004, OR = 3.852, CI: 1.550-9.569), pork consumption (p T. gondii infection. Our results show that there is a relationship between toxoplasmosis and schizophrenia.
  • 关键词:Toxoplasma Gondii; Schizophrenia; Seroprevalence; Socio-Demographic Risk Factors; Environmental Risk Factors
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