期刊名称：Journal of Theoretical and Applied Information Technology
印刷版ISSN：1992-8645
电子版ISSN：1817-3195
出版年度：2012
卷号：46
期号：2
页码：0790-0793
出版社：Journal of Theoretical and Applied
摘要：The aim of this paper is to analyze the impacts of the pregnant women�s ages and the gestational weeks on the serological prenatal screening in Down�s syndrome, and then explore and identify the best range of the ages of the pregnant women and the gestational weeks. During 2009 to 2011, there are 3162 pregnant women who had accepted to receive the screening of Down�s syndrome, giving the birth in the hospital and being interviewed in Tangshan. During the week fifteenth to the week twenty-first, examine the typical factors of maternal serum, AFP and β-HCG, through the risk evaluation software of Down�s syndrome. For the high risk case, the amnionic paracentesis is required for diagnosis. Compare the high risk rate of Down�s syndrome between the different groups in different ages. The results of the high risk rate of Down�s syndrome got from the different gestational weeks and the false rate of the screening are also needed to be examined. The obtained results can help to improve the accurate rate of the diagnosis, meanwhile reducing the rate of misdiagnosis.
