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  • 标题:Irreversible electroporation for the treatment of pancreatic neuroendocrine tumors
  • 本地全文:下载
  • 作者:Papamichail, Michail ; Ali, Amir ; Pizanias, Michail
  • 期刊名称:Korean Journal of Hepato-Biliary-Pancreatic Surgery
  • 印刷版ISSN:1738-6349
  • 出版年度:2016
  • 卷号:20
  • 期号:3
  • 页码:116-120
  • DOI:10.14701/kjhbps.2016.20.3.116
  • 语种:English
  • 出版社:by The Korean Association of Hepato-Biliary-Pancreatic Surgery
  • 摘要:Backgrounds/Aims

    Resection or enucleation is currently the treatment of choice for small pancreatic neuroendocrine tumors (NETs). Irreversible electroporation is a novel ablative method that is used for locally advanced pancreatic adenocarcinoma, but little data exists for its use for pancreatic NETs. We report an early experience of IRE for early pancreatic NETs.

    Methods

    Between April 2014 and March 2015, 3 patients with small (<2 cm) pancreatic NETs were treated with percutaneous IRE.

    Results

    There were no adverse effects during the procedure. Mean hospital stay was 2.6 days. All patients remained disease free on 12-19 months follow up. One patient developed recurrent pancreatitis with pseudocyst formation.

    Conclusions

    IRE for small tumors of the pancreas is practical and may offer advantages over other thermal ablative techniques, since it preserves vital structures such as blood vessels, bile and pancreatic ducts. Further data regarding the long term disease free interval is required to establish efficacy.

  • 关键词:Irreversible electroporation (IRE); Pancreatic neuroendocrine tumors; Non-thermal ablation
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