The effects of ether and halothane anesthesia, and surgery on blood sugar level in children were studied in twelve patients, Six patients were anesthetized with ether and other six patients with halothane. Blood samples were taken two times through a catheter in the external jugular vein after intravenous injection of pentothal 6 mg/kg and succinylcholine 1mg/kg during the anesthesia and. surgical procedure. Blood sugar was measured with the orthotoluidine method. The mean value of blood sugar in the ether group was elevated significantly from 68 mg/100 inl to 92. 2 mg/100 ml and also in the halothane group it was elevated' from 68. 8 mg/l00 ml to 81 mg/100 ml, with a significant difference that the blood sugar level was higher in the ether group than in the halothane group. Results were also compared with the hyperglycemic response to different types of surgery. The value of blood sugar under general anesthesia during intra-abdominal, body surface and other surgery was measured. The hyperglycemic response to intra-abdominal surgery was the largest and the next was in other surgery, and in body surface surgery it was smallest, so it was shown there is a relationship between the degree of trauma and the rise in blood sugar.