Frequently local anesthesia csn be a more useful method than general anesthesia for simple operations, but numerous complications have been reported. High blood level of the drug injected causes the majority of reactions, probably 99% or better, and alIergy to the drug employed comprises a very small fraction, probably less than 1%. The authors treated 5 cases of cardiopulmonary arrest and convulsion due to generalized toxicity of local anesthetics. In 5 cases, 4 patients recovered, but one patient expired. It can be emphasized that careful administration of agents and proper treatment for convuIsion is indicated.