出版社:Shahid Sadoughi University of Medical Sciences, yazd, Iran
摘要:Background: Malathion (MAL) is a choice insecticide in the stored grain in different countries. The aim of the present study is to evaluate toxicological effects of 30-day intake of MAL on the male reproductive system of Wistar rats. Methods: This research was ethically approved by the local authority at Faculty of Medicine, Monastir, Tunisia. Three MAL treated groups received 1 ml corn oil contain-ing 1.3, 13.7, and 137 mg/kg body weight/day, respectively. Body and testes weights, testosterone, Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) levels were measured. Histopathological sections were prepared from testes of animals and stained with hematoxylin and eosin and also Masson trichrome. Statistical analysis was done using SPSS for windows version 10. Results: A meaningful decrease (p 0.05) was found between body weight of control and treatment groups. All the three MAL-treated rats had significantly (p