期刊名称：IMPACT : International Journal of Research in Applied, Natural and Social Sciences
印刷版ISSN：2347-4580
电子版ISSN：2321-8851
出版年度：2017
卷号：5
期号：1
页码：93-98
语种：English
出版社：IMPACT Journals
摘要：Bacterial artificial chromosomes (BAC) are one of the most important research tools being significantly proven to efficiently hold up to 350 kb of DNA to be cloned. The development of BAC has been proven an ambitious success story for human genome project, in genomic DNA libraries and physical map construction for genomic sequencing. The salient feature of Escherichia coli derived F-factor is most basic requirement for BAC, which helps in maintenance of DNA clones and easy manipulation of cloned DNA. The following paper accounts details on BAC.
