文章基本信息

标题：Long-term exposure to diesel engine exhaust induced lung function decline in a cross sectional study
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作者：Li Ping ZHANG ; Xiao ZHANG ; Hua Wei DUAN 等
期刊名称：Industrial Health
印刷版ISSN：0019-8366
电子版ISSN：1880-8026
出版年度：2017
卷号：55
期号：1
页码：13-26
DOI：10.2486/indhealth.2016-0031
出版社：National Institute of Occupational Safety and Health
摘要：
To clarify the effects of lung function following exposure to diesel engine exhaust (DEE), we recruited 137 diesel engine testing workers exposed to DEE and 127 non-DEE-exposed workers as study subjects. We performed lung function tests and measured cytokinesis-block micronucleus (CBMN) cytome index and levels of urinary polycyclic aromatic hydrocarbons (PAHs) metabolites. There was a significant decrease of forced expiratory volume in 1 second (FEV₁), ratio of forced expiratory volume in 1 second to forced vital capacity (FEV₁/ FVC), maximal mid expiratory flow curve (MMF), forced expiratory flow at 50% of FVC (FEF_50%), and forced expiratory flow at 75% of FVC (FEF_75%) in the DEE-exposed workers than non-DEE-exposed workers (all p 75% were associated with the increasing levels of PAHs metabolites ( p 1, FEV₁/FVC, MMF, FEF_50%, and FEF_75% with CBMN cytome index (all p
关键词：Diesel engine exhaust;Lung function;The cytokinesis-block micronucleus cytome index;Urinary mono-hydroxylated polycyclic aromatic hydrocarbons;Long-term exposure