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  • 标题:Analyzing Competing Risk Data Using the R timereg Package
  • 本地全文:下载
  • 作者:Thomas H. Scheike ; Mei-Jie Zhang
  • 期刊名称:Journal of Statistical Software
  • 印刷版ISSN:1548-7660
  • 电子版ISSN:1548-7660
  • 出版年度:2011
  • 卷号:38
  • 期号:1
  • 页码:1-15
  • 语种:English
  • 出版社:University of California, Los Angeles
  • 摘要:In this paper we describe flexible competing risks regression models using the comp.risk() function available in the timereg package for R based on Scheike et al. (2008). Regression models are specified for the transition probabilities, that is the cumulative incidence in the competing risks setting. The model contains the Fine and Gray (1999) model as a special case. This can be used to do goodness-of-fit test for the subdistribution hazards’ proportionality assumption (Scheike and Zhang 2008). The program can also construct confidence bands for predicted cumulative incidence curves. We apply the methods to data on follicular cell lymphoma from Pintilie (2007), where the competing risks are disease relapse and death without relapse. There is important non-proportionality present in the data, and it is demonstrated how one can analyze these data using the flexible regression models.
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