Usability of software applications is a key to success of any system and the technology is best care because it is not susceptible to forget or to damage. The main aim of the proposed system application is to help two important categories of the society they are elderly and Alzheimer’s patients, these two categories shared in one recipe which is a forgetful. Proposed application gives elderly and Alzheimer’s patients an opportunity to have small memory which can help them to remember tasks, events, medications and people. It is a great opportunity to learn what makes a proposed application good. Which may contribute to the prevention of progression of the disease rapidly. In this study Technology Acceptance Model has been designed to investigate the end-user acceptance of designing Proposed Mobile Reminder System. The purpose of this study is to design a quantitative approach based on the technology acceptance model questionnaire as its primary research methodology. It utilized a quantitative approach based a Technology Acceptance Model (TAM) to evaluate the designing Proposed Mobile Reminder System. The related constructs for evaluation are: Perceived of Usefulness, Perceived Ease of Use, User Satisfaction and Attribute of Usability. All these constructs are modified to suit the context of the study. Moreover, this study outlines the details of each construct and its relevance toward the research issue. The outcome of the study represents series of approaches that will apply for checking the advantages of proposed system by helping the target groups to remember what they may forget, and helping care providers to save time and effort.