期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1992
卷号：12
期号：2
页码：77-83
DOI：10.3164/jcbn.12.77
出版社：The Society for Free Radical Research Japan
摘要：Whether or not the feeding of air-oxidized oil to rat dams during the period of gestation or lactation affects the lipid peroxide contents in their offspring was studied. Rat dams were given a diet containing 4g soybean oil or air-oxidized soybean oil/100g diet during gestation. Whole body lipid peroxides, thiobarbituric acid-reactive substances (TBARS) determined as malondialdehyde, in newborn pups from dams fed the air-oxidized oil diet were not different from those from dams fed the unoxidized oil diet. When dams were given the oxidized oil diet during lactation, whole body TBARS contents in suckling pups increased sharply in the 10-day-old neonate and decreased until 21 days old. However, these trends were not affected by the amounts of air-oxidized soybean oil nor the unoxidized oil diet. These findings indicate that a maternal diet containing air-oxidized oil during gestation or lactation does not affect the whole body lipid peroxides in neonatal rats.
关键词：air-oxidized oil;rat dam;whole body TBARS;neonatal rat
