期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1995
卷号：18
期号：1
页码：1-9
DOI：10.3164/jcbn.18.1
出版社：The Society for Free Radical Research Japan
摘要：Soluble dietary fibers have been shown to reduce total plasma cholesterol and LDL-cholesterol, the two important risk factors for coronary heart disease. Multiple mechanisms appear to be involved in the hypocholesterolemic response, and data indicate that the profile of operating mechanisms may vary considerably among different dietary fiber sources. The mechanisms which have been suggested include binding of bile acids and interference with their enterohepatic circulation, interference with micelle formation, and reduced hepatic cholesterol synthesis. An examination of hypocholesterolemic action of dietary pectin indicates that this effect is due to a shift of cholesterol from plasma to the hepatic pools.
