期刊名称:Journal of Clinical Biochemistry and Nutrition
印刷版ISSN:0912-0009
电子版ISSN:1880-5086
出版年度:1995
卷号:19
期号:2
页码:63-70
DOI:10.3164/jcbn.19.63
出版社:The Society for Free Radical Research Japan
摘要:Aqueous extract of Emblica officinalis was found to be a potent inhibitor of lipid peroxide formation and scavenger of hydroxyl and superoxide radicals in vitro . The amount of the fresh pulp needed to inhibit 50% of lipid peroxidation was 1, 000μg/ml in the Fe2+/ascorbate system and 640μg/ml in the Fe3+/ADP-ascorbate one. The concentration needed for 50% inhibition of superoxide-scavenging activity was 107μg/ml in the method involving photoreduction of riboflavin and 232μg/ml in the xanthine-xanthine oxidase method, and that for hydroxyl radical scavenging (deoxyribose degradation method) was 3, 400μg/ml. An indigenous drug preparation containing Emblica officinalis , used in India as a health tonic, was also found to have a potent antioxidant activity. The antioxidants present in Emblica officinalis were aqueous soluble, but partially extractable with ether, and were heat stable.