期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1995
卷号：19
期号：3
页码：175-182
DOI：10.3164/jcbn.19.175
出版社：The Society for Free Radical Research Japan
摘要：The effect of catechin on lipid metabolism was investigated in rats. Catechin at doses ranging from 0.1 to 100mg/kg BW was administered daily by gastric incubation to rats fed a normal laboratory diet. Catechin exerted no negative impact of food intake and thereby no retardation of growth. Maximum hypocholesterolemic activity was detected at a dose of 10mg/kg BW/day. The hypocholesterolemic activity of the drug was found not to be due to a decreased cholesterogenesis, but to a higher rate of degradation and excretion of cholesterol.
