期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1996
卷号：20
期号：3
页码：173-180
DOI：10.3164/jcbn.20.173
出版社：The Society for Free Radical Research Japan
摘要：Flavonoids are potent inhibitors of the oxidative modification of low-density lipoprotein (LDL), and foods containing these compounds have been shown to be negatively associated with coronary heart disease (CHD). Flavonoids reduce the formation of free radicals and protect or regenerate other antioxidants; or alternatively, they chelate divalent metal ions. Isoflavones may act in a manner similar to estrogen in that they lower LDL and in this way confer protection against CHD. Less is known about other minor dietary constituents, such as boron, which is widespread in fruits and vegetables. Boron may have an impact on CHD by inducing small increases in the concentration of plasma estrogen.
