期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1996
卷号：21
期号：3
页码：165-170
DOI：10.3164/jcbn.21.165
出版社：The Society for Free Radical Research Japan
摘要：We studied the influence of semiconductor laser irradiation on the cultured human epidermal keratinocytes and measured cell viability and the concentration of interleukin-1α (IL-1α) in the medium of irradiated cell cultures. We found that the number of viable cells in the cultures was significantly increased by giving semiconductor laser irradiation for 15s (115.0±0.5%), 20s (112.0±1.0%) compared with the number in the nonirradiated cultures ( p <0.01). The production of IL-1α by cultured cells was increased by the laser irradiation for 20s (35.8±5.5pg/ml) compared with the control (27.0±5.6pg/ml) after a 12-h incubation period ( p <0.01). These results imply that low-power laser irradiation has significant biological effects on human keratinocytes.
关键词：semiconductor laser;cultured human keratinocytes;interleukin-1α
