首页    期刊浏览 2025年02月18日 星期二
登录注册

文章基本信息

  • 标题:Fatty Acid Esters of Sitosterol 3β-Glucoside from Soybeans and Tempe (Fermented Soybeans) as Antiproliferative Substances
  • 本地全文:下载
  • 作者:Serafim KIRIAKIDIS ; Stavroula STATHI ; Hem Chandra JHA
  • 期刊名称:Journal of Clinical Biochemistry and Nutrition
  • 印刷版ISSN:0912-0009
  • 电子版ISSN:1880-5086
  • 出版年度:1997
  • 卷号:22
  • 期号:3
  • 页码:139-147
  • DOI:10.3164/jcbn.22.139
  • 出版社:The Society for Free Radical Research Japan
  • 摘要:In the present study we isolated and identified two mixtures of fatty acid esters of β-sitosterol glucoside from soybeans and its fermented product, tempe. The mixtures of glucolipids occurring in soybeans and tempe are unseparable and possess the following structures: sitosterol-3-O-β-D-(6′-O-palmitoyl/-linoleoyl)- and sitosterol-3-O-β-D-(6′-O-palmitoyl/-stearoyl)-glucopyranoside, respectively. Since tempe constituents show antitumor activity, we tested these glucolipids against mouse myeloma cells (tumor cells). The tempe glucolipid mixture showed higher inhibition (95.3%) at the 50μg/ml concentration than the soybean one. The maximum activity of the soybean glucolipid mixture was (96%) at 100μg/ml.
  • 关键词:fermented soybean;sitosterol;sitosterol glucoside;sitosterol-3-O-β-D-(6′-O-palmitoyl)-glucopyranoside;sitosterol-3-O-β-D-(6′-O-stearoyl)-glucopyranoside;sitosterol-3-O-β-D-(6′-0-linoleoyl)-glucopyranoside;mouse myeloma cells X63-Ag8.653;antitumor activity
国家哲学社会科学文献中心版权所有