期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1997
卷号：22
期号：3
页码：155-161
DOI：10.3164/jcbn.22.155
出版社：The Society for Free Radical Research Japan
摘要：Feeding of gallic acid elevated the hepatic levels of glutathione peroxidase (GPx) and catalase, whereas NADPH-mediated microsomal lipid peroxidation was found to be unaltered. However, in lungs, besides a significant increase in reduced glutathione (GSH) and GPx, there was an inhibition of enzymatic lipid peroxidation in post-mitochondrial supernatant. On the other hand, propylgallate increased the hepatic GPx and GSH as well as inhibited hepatic microsomal and pulmonary lipid peroxidation. It seems that propylgallate is a better antioxidant than gallic acid since unlike gallic acid it protects both liver and lungs from the damaging action of the free radical-mediated process of lipid peroxidation.
