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  • 标题:Change in Serum Lipid Hydroperoxides in Thermal Injury
  • 本地全文:下载
  • 作者:Kunio YAGI ; Jin-Yang GUAM ; Qian SUN
  • 期刊名称:Journal of Clinical Biochemistry and Nutrition
  • 印刷版ISSN:0912-0009
  • 电子版ISSN:1880-5086
  • 出版年度:1997
  • 卷号:23
  • 期号:3
  • 页码:139-143
  • DOI:10.3164/jcbn.23.139
  • 出版社:The Society for Free Radical Research Japan
  • 摘要:The concentration of serum lipid hydroperoxides of male rats of the Wistar strain that had received thermal injury on their backs was measured by the hemoglobin-methylene blue (Hb-MB) method. The concentration increased significantly 0.5h after the injury, was higher than that of the normal level until 5h, and decreased to the normal concentration by 7h after the injury. The lipid peroxide level measured by the thiobarbituric acid (TBA) method increased up to 5h after the injury, and then maintained at a higher level than normal for 48h. Thus, the measurement of the total concentration of serum lipid hydroperoxides by the Hb-MB method is useful to detect lipid peroxidation in the early period after the injury, and serum lipid peroxide level measured by the TBA method may reflect the progress of systemic dysfunction.
  • 关键词:lipid hydroperoxides;serum;thermal injury;rat
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