期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1987
卷号：3
期号：2
页码：87-94
DOI：10.3164/jcbn.3.87
出版社：The Society for Free Radical Research Japan
摘要：When cultured aortic smooth muscle cells were incubated with linoleic acid hydroperoxide and then with low density lipoprotein, marked deposition of lipids in the cells, viz., formation of lipid-laden cells, occurred; while incubation with either linoleic acid hydroperoxide alone or low density lipoprotein alone scarcely provoked the deposition of lipids in the cells. In the case of macrophages derived from monocytes, their incubation with low density lipoprotein preincubated with linoleic acid hydroperoxide resulted in formation of typical lipid-laden cells, even though incubation of the cells with either linoleic acid hydroperoxide alone or intact low density lipoprotein alone scarcely produced lipid-laden cells.
关键词：lipid-laden cells;aortic smooth muscle cells;macrophages;linoleic acid hydroperoxide;low density lipoprotein
