期刊名称:Journal of Clinical Biochemistry and Nutrition
印刷版ISSN:0912-0009
电子版ISSN:1880-5086
出版年度:1987
卷号:3
期号:2
页码:135-142
DOI:10.3164/jcbn.3.135
出版社:The Society for Free Radical Research Japan
摘要:Arginase activity in the erythrocyte showed lower values in cases of cerebral and myocardial infarctions than in normal cases. To explore this phenomenon we studied the effect of arginase on platelet aggregation. It was demonstrated that the arginase possesses the inhibitory activity toward platelet aggregation: it inhibits the formation of the platelet-thrombus due to arachidonic acid in vivo by raising its concentration in the erythrocyte. Thus it appears that the arginase in erythrocytes is concerned with the inhibition of thrombus formation.