期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：2003
卷号：33
期号：1
页码：7-11
DOI：10.3164/jcbn.33.7
出版社：The Society for Free Radical Research Japan
摘要：The protective effects of L-arginine in combination with L-lysine on lipid metabolism were examined against isoproterenol-induced myocardial infarction in rats. The levels of cholesterol, triacylglycerols and free fatty acids were estimated both in serum and the myocardial tissue.The levels of LDL- and HDL-cholesterol in serum and phospholipids in the myocardial tissues were also estimated in the normal and experimental rats. The rats administered isoproterenol (150mg kg-1 daily, intraperitoneally) showed significant changes in the lipid components. Prior oral treatment with L-arginine (250mg kg-1 daily) along with L-lysine (5mg kg-1 daily) in alleviating isoproterenol-induced biochemical disturbances with respect to lipid metabolism has been the hallmark of the study.
