期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1988
卷号：4
期号：3
页码：241-248
DOI：10.3164/jcbn.4.241
出版社：The Society for Free Radical Research Japan
摘要：Fasting blood sugar, triglyceride, cholesterol, lipoprotein cholesterol, and urinary hydroxyproline levels were determined in insulin-dependent diabetic (IDDM) and non-insulin-dependent diabetic (NIDDM) patients. Appreciable hyperglycemia and hypertriglyceridemia were noticed in all diabetics. Influence of sex was noticed in cholesterol levels and its fractions. IDDM males did not differ appreciably from their age- and sex-matched controls with respect to cholesterol and its fractions, whereas NIDDM males registered a significant change in low density lipoprotein (LDL)-cholesterol when compared with their sex- and age-matched controls. IDDM males showed a lower level of cholesterol and its fractions than the NIDDM males. Both IDDM and NIDDM female diabetics exhibited an appreciable increase in total cholesterol and LDL-cholesterol when compared with their sex- and age-matched controls. The female diabetics in general showed a higher level of total cholesterol, LDL-cholesterol, and triglyceride than the males. Urinary excretion of hydroxyproline showed an increase in the case of females of both IDDM and NIDDM types when compared with the corresponding male patients. However there was no appreciable difference among the different hydroxyproline fractions between males and females of either type.
