期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1988
卷号：4
期号：3
页码：249-254
DOI：10.3164/jcbn.4.249
出版社：The Society for Free Radical Research Japan
摘要：Immunohistochemical distribution of vitamin B12 R-binder, an immunologically distinct vitamin B12-binding protein, was studied in human skin tissues. Positive staining for R-binder was found in normal eccrine glands, syringoma, eccrine poroma, and genital Paget's disease. It is speculated that R-binder plays a role in the local defense mechanism by inhibiting bacterial overgrowth.
