期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1989
卷号：6
期号：1
页码：57-63
DOI：10.3164/jcbn.6.57
出版社：The Society for Free Radical Research Japan
摘要：The K value=[AFR]2/[RAsA] [DAsA ] (RAsA, reduced form of ascorbic acid; DAsA, oxidized form of ascorbic acid; AFR, ascorbate free radical), and changes in AFR concentration in human serum were examined after exposure to oxygen radicals. After the exposure, RAsA decreased, DAsA increased, and K value increased. Since the K value is constant in healthy subjects, it is regarded to be a clinical index to indicate the attack of oxygen radicals in living system. Whereas changes in AFR concentration in ascorbate solutions showed a one-way decrease after an initial increase, changes in serum were those of a persistent pattern with slight fluctuation after the initial increase. The difference was found to be attributable to the presence of a serum factor that inhibits ascorbate oxidation.
