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  • 标题:Relationships among Plasma Lipids, Lipoproteins, and Platelet Aggregation Profiles in Diabetes
  • 本地全文:下载
  • 作者:Sunita M. JETHMALANI ; Gomathy VISWANATHAN ; John M. NORONHA
  • 期刊名称:Journal of Clinical Biochemistry and Nutrition
  • 印刷版ISSN:0912-0009
  • 电子版ISSN:1880-5086
  • 出版年度:1989
  • 卷号:6
  • 期号:3
  • 页码:257-264
  • DOI:10.3164/jcbn.6.257
  • 出版社:The Society for Free Radical Research Japan
  • 摘要:We compared plasma lipids, lipoproteins, platelet aggregation, plasma lipase activity, age, and body mass index (BMI) between patients with non-insulin-dependent diabetes mellitus and non-diabetic controls. Diabetic subjects showed significantly higher levels of plasma total triglycerides (TG) and very-low-density lipoprotein cholesterol (VLDL-C) and significantly increased platelet aggregability. The total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-C) ratio was also significantly higher consequent to the significantly lower HDL-C levels in the diabetic subjects when compared with non-diabetic controls. The diabetic group showed positive significant correlations between TC and low-density lipoprotein cholesterol (LDL-C), HDL-C and plasma lipase activity, and TG and TC/HDL-C ratio, whereas significant inverse correlations were observed between TG and HDL-C, HDL-C and TC/HDL-C ratio. Platelet aggregation did not correlate significantly with any of the metabolic variables studied in this group.
  • 关键词:lipids;lipoproteins;platelet aggregation;diabetes
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