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  • 标题:Spontaneous Clearing of Lens Opacity in a New Substrain of Rats with Inherited Cataract
  • 本地全文:下载
  • 作者:Nobuo IHARA ; Ikuko WATANABE ; Sadaaki KOMURA
  • 期刊名称:Journal of Clinical Biochemistry and Nutrition
  • 印刷版ISSN:0912-0009
  • 电子版ISSN:1880-5086
  • 出版年度:1990
  • 卷号:8
  • 期号:2
  • 页码:103-110
  • DOI:10.3164/jcbn.8.103
  • 出版社:The Society for Free Radical Research Japan
  • 摘要:A substrain of rats with inherited cataracts was established as an inbred strain on the basis of the prominent feature that spontaneous clearing of lens opacity occurs after the completion of the cataract. The clearing of lens opacity in these rats was confirmed by the observation of the morphological changes in lens fibers by light microscopy, and supported by the findings that the contents of water, water-soluble proteins, and high molecular weight proteins returned nearly to normal levels. This strain of rats was termed the “ICRL” rat. Another substrain, which is characterized by persistent cataract, was also established as an inbred strain and termed the “ICRF” rat.
  • 关键词:inherited cataract;ICRL rat;clearing of lens opacity;ICRF rat
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