期刊名称:Journal of Clinical Biochemistry and Nutrition
印刷版ISSN:0912-0009
电子版ISSN:1880-5086
出版年度:1990
卷号:9
期号:3
页码:179-184
DOI:10.3164/jcbn.9.179
出版社:The Society for Free Radical Research Japan
摘要:Epinephrine and norepinephrine, when either formed a complex with iron, were able to induce lipid peroxidation in rat liver microsomes. The microsomal lipid peroxidation induced by them was NADPH-dependent. Adrenochrome, an oxidation product of epinephrine, was also able to induce microsomal lipid peroxidation in the presence of iron, but in this case it was mainly NADPH-independent. Catecholamines can be deleterious to biological systems, if they form complexes with iron and thus induce lipid peroxidation to some extent.