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  • 标题:The structure of cerebrosides in Gaucher's disease
  • 本地全文:下载
  • 作者:G. V. Marinetti ; T. Ford ; Elmer Stotz
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1960
  • 卷号:1
  • 期号:3
  • 页码:203-207
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:Crystalline cerebrosides were isolated from the spleen of a woman with Gaucher's disease. The cerebrosides accounted for 38 per cent of the total spleen lipids and 0.89 per cent of the fresh spleen. The sugar moiety of the cerebrosides was found to be glucose and its position of attachment was establihed to be on the primary hydroxyl group of sphingosine. The double bond in the sphingosine moiety had the trans configuration. The fatty acids of the cerebroside were determined by gas chromatography and paper chromatography and found to be mainly lignoceric, behenic, and palmitic acid. Small amounts of arachidic and stearic acids were also present.
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