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  • 标题:Biosynthesis of presqualene pyrophosphate by liver microsomes
  • 本地全文:下载
  • 作者:H. C. RILLING
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1970
  • 卷号:11
  • 期号:5
  • 页码:480-485
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:Microsomes from rat liver have been shown to synthesize a squalene precursor from farnesyl pyrophosphate. This intermediate is identical with presqualene pyrophosphate, a 30-carbon cyclopropane containing pyrophosphate ester that had previously been isolated from yeast. The squalene precursor was found to be tightly, but not covalently, bound to microsomes.
  • 关键词:squalene biosynthesis ; farnesyl pyrophosphate
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