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  • 标题:An improved procedure for the synthesis of glycine and taurine conjugates of bile acids.
  • 本地全文:下载
  • 作者:K Y Tserng ; D L Hachey ; P D Klein
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1977
  • 卷号:18
  • 期号:3
  • 页码:404-407
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:Glycine and taurine conjugates of 5beta-cholanic acids have been synthesized using improved procedures based on the peptide coupling reagent, N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline. The conjugates are obtained in chromatographically pure form in yields higher than 90%. The use of this procedure in the large scale preparation of cholyl[1,2-13C2]glycine is described.
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